Yoichi Shinkai Selected Research

Kleefstra Syndrome

7/2021	Derepression of inflammation-related genes link to microglia activation and neural maturation defect in a mouse model of Kleefstra syndrome.
3/2013	Hippocampal dysfunction in the Euchromatin histone methyltransferase 1 heterozygous knockout mouse model for Kleefstra syndrome.

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Yoichi Shinkai Research Topics

Disease

4	Neoplasms (Cancer) 01/2021 - 06/2009
2	Genomic Instability 01/2023 - 01/2020
2	Autism Spectrum Disorder 12/2021 - 01/2014
2	Intellectual Disability (Idiocy) 07/2021 - 03/2010
2	Kleefstra Syndrome 07/2021 - 03/2013
2	Carcinogenesis 11/2020 - 09/2006
2	Hypoxia (Hypoxemia) 10/2014 - 09/2006
1	Sickle Cell Anemia (Hemoglobin S Disease) 12/2023
1	Male Infertility (Male Sterility) 01/2022
1	Neuritis (Polyneuritis) 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 01/2021
1	Liver Neoplasms (Liver Cancer) 01/2021
1	Parkinson Disease (Parkinson's Disease) 01/2021
1	B-Cell Leukemia (Leukemia, B Cell) 01/2019
1	Leukemia 01/2018
1	Hypersensitivity (Allergy) 01/2018
1	Immediate Hypersensitivity 01/2018
1	Embryonal Carcinoma 10/2014
1	Seminoma 10/2014
1	Endodermal Sinus Tumor (Endodermal Sinus Tumors) 10/2014
1	Autistic Disorder (Autism) 01/2014
1	Schizophrenia (Dementia Praecox) 01/2014
1	Carcinoma (Carcinomatosis) 01/2013
1	Chromosome Aberrations (Chromosome Abnormalities) 06/2010
1	Type 2 Diabetes Mellitus (MODY) 08/2009
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 08/2009
1	Obesity 08/2009
1	Hemorrhage 01/2006
1	Reye Syndrome (Reye's Syndrome) 01/2006
1	Prader-Willi Syndrome (Syndrome, Prader-Willi) 04/2003

Drug/Important Bio-Agent (IBA)

8	Histone MethyltransferasesIBA 01/2021 - 04/2003
6	Histones (Histone)IBA 12/2021 - 04/2003
4	MethyltransferasesIBA 07/2021 - 01/2014
3	EnzymesIBA 12/2021 - 09/2006
3	Proteins (Proteins, Gene)FDA Link 07/2021 - 09/2006
3	Lysine (L-Lysine)FDA Link 07/2021 - 09/2006
3	ChromatinIBA 01/2019 - 06/2010
2	Retroelements (Retrotransposon)IBA 01/2022 - 01/2020
2	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 06/2009
2	EuchromatinIBA 03/2013 - 03/2010
1	GlobinsIBA 12/2023
1	HeterochromatinIBA 01/2023
1	SynucleinsIBA 01/2021
1	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 01/2021
1	UNC 0638IBA 01/2021
1	PrionsIBA 01/2021
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2021
1	TransposasesIBA 01/2019
1	Syk KinaseIBA 01/2018
1	Hexosaminidases (Hexosaminidase)IBA 01/2018
1	anti-IgE antibodiesIBA 01/2018
1	Immunoglobulin E (IgE)IBA 01/2018
1	Immunoglobulin Fab FragmentsIBA 01/2018
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2013
1	Nucleosomes (Nucleosome)IBA 06/2010
1	Glucose (Dextrose)FDA LinkGeneric 08/2009
1	Histone DemethylasesIBA 08/2009
1	AntigensIBA 06/2009
1	tributyl phosphate (TBP)IBA 01/2006
1	human TXNIP proteinIBA 01/2006
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2006

Therapy/Procedure

1	Aftercare (After-Treatment) 01/2021